DisVis is a software designed to visualize and quantify the accessible interaction space defined by distance restraints between biomolecules. It performs a systematic 6-dimensional search of the translational and rotational degrees of freedom to determine how many complexes are consistent with the original restraints. In addition, DisVis allows to identify false positive restraints.
Besides the application software, the DisVis web portal provides automated pre- and post-processing, the compute, storage and job scheduling and monitoring for running the application. This means that the researcher does not have to worry about application porting nor about procuring the necessary compute infrastructure.
DisVis is free to use but requires registration (which is also free).
DisVis has been implemented as a web portal, harvesting both local CPU resources and GPGPU-accelerated EGI High-Throughput Compute resources. The use of a web portals eliminates the need for any local software installation and guarantees a robust user-experience through a reliable framework.
DisVis is a service provided by the Bijvoet Center, Utrecht University.
DisVis was developed under the WestLife, BioExcel and MoBrain projects.
van Zundert et al. 2016. The DisVis and PowerFit web servers: Explorative and Integrative Modeling of Biomolecular Complexes. Journal of Molecular Biology. doi: 10.1016/j.jmb.2016.11.032. (Full text, Open Access)